__ sapiens

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Possible Answers: HOMO.

Last seen on: –LA Times Crossword 24 Jan 22, Monday
LA Times Crossword 6 May 21, Thursday
LA Times Crossword 14 Jul 20, Tuesday
LA Times Crossword 22 Oct 18, Monday
The Washington Post Crossword – Oct 22 2018

Random information on the term “HOMO”:

In chemistry, frontier molecular orbital theory is an application of MO theory describing HOMO / LUMO interactions.

In 1952, Kenichi Fukui published a paper in the Journal of Chemical Physics titled “A molecular theory of reactivity in aromatic hydrocarbons.” Though widely criticized at the time, he later shared the Nobel Prize in Chemistry with Roald Hoffmann for his work on reaction mechanisms. Hoffman’s work focused on creating a set of four pericyclic reactions in organic chemistry, based on orbital symmetry, which he coauthored with Robert Burns Woodward, entitled “The Conservation of Orbital Symmetry.”

Fukui’s own work looked at the frontier orbitals, and in particular the effects of the Highest Occupied Molecular Orbital (HOMO) and the Lowest Unoccupied Molecular Orbital (LUMO) on reaction mechanisms, which led to it being called Frontier Molecular Orbital Theory (FMO Theory). He used these interactions to better understand the conclusions of the Woodward–Hoffmann rules.

HOMO on Wikipedia