___ Tac (brand of breath mints)

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Possible Answers: Tic.

Last seen on: –Daily Celebrity Crossword – 2/11/19 Movie Monday
Daily Celebrity Crossword – 2/24/18 Smartypants Saturday

Random information on the term “Tic”:

Causes and origins of Tourette syndrome have not been fully elucidated. Tourette syndrome (also called “Tourette’s syndrome”, “Tourette’s disorder”, “Gilles de la Tourette syndrome”, “GTS” or “TS”) is an inherited neurological disorder with onset in childhood, characterized by the presence of multiple motor tics and at least one phonic tic, which characteristically wax and wane. Tourette’s syndrome occurs along a spectrum of tic disorders, which includes transient tics and chronic tics.

The exact cause of Tourette’s is unknown, but it is well established that both genetic and environmental factors are involved. Genetic studies have proved that the overwhelming majority of cases of Tourette’s are inherited, although the exact mode of inheritance is not yet known, and no gene has been identified. Tics are believed to result from dysfunction in the thalamus, basal ganglia, and frontal cortex of the brain, involving abnormal activity of the brain chemical, or neurotransmitter, dopamine. Other studies demonstrate that in addition to dopamine, multiple neurotransmitters, like serotonin, GABA, glutamate, and histamine (H3-receptor), are involved.

Tic on Wikipedia