Abet

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Possible Answers: AID, HELP, SECOND, BEINCAHOOTSWITH.

Last seen on: –Universal Crossword – Dec 9 2018
-The Telegraph – Quick Crossword – June 9 2018
-Mirror Cryptic Crossword December 1 2017
-Mirror Classic Crossword December 1 2017

Random information on the term “AID”:

5JJ4

57379

11628

ENSG00000111732

ENSMUSG00000040627

Q9GZX7

Q9WVE0

NM_020661
NM_001330343

NM_009645

NP_001317272
NP_065712

NP_033775.1
NP_033775

Activation-induced cytidine deaminase, also known as AICDA and AID, is a 24 kDa enzyme which in humans is encoded by the AICDA gene. It creates mutations in DNA by deamination of cytosine base, which turns it into uracil (which is recognized as a thymine). In other words, it changes a C:G base pair into a U:G mismatch. The cell’s DNA replication machinery recognizes the U as a T, and hence C:G is converted to a T:A base pair. During germinal center development of B lymphocytes, AID also generates other types of mutations, such as C:G to A:T. The mechanism by which these other mutations are created is not well-understood.

In B cells in the lymph nodes, AID causes mutations that produce antibody diversity, but that same mutation process leads to B cell lymphoma.

AID on Wikipedia

Random information on the term “HELP”:

In computing, help is a command in various command line shells such as COMMAND.COM, cmd.exe, Bash, 4DOS/4NT, Windows PowerShell, Singularity shell, Python and GNU Octave. It provides online information about available commands and the shell environment. The command is also available in the DEC RT-11 operating system. On Unix, the command is part of the Source Code Control System and prints help information for the SCCS commands.

Arguments:

The help command is available in MS-DOS 5.x and later. If no arguments are provided, the command lists the contents of DOSHELP.HLP. In MS-DOS 6.x this command exists as FASTHELP. In DR-DOS, HELP is a batch file that launches DR-DOS’ internal help program, DOSBOOK.

The 4DOS/4NT help command uses a text user interface to display the online help.

Used without parameters, help lists and briefly describes every system command. Windows NT-based versions use MS-DOS 5 style help. Versions before Windows Vista also have a Windows help file (NTCMDS.HLP or NTCMDS.INF) in a similar style to MS-DOS 6.

HELP on Wikipedia