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Possible Answers: RMS, BRS, EIK.

Last seen on: –Wall Street Journal Crossword – August 29 2022 – Hair Care
Wall Street Journal Crossword – June 09 2020 – Fancy Pants

Random information on the term “RMS”:

Rhabdomyosarcoma, or RMS, is an aggressive and highly malignant form of cancer that develops from skeletal (striated) muscle cells that have failed to fully differentiate. It is generally considered to be a disease of childhood, as the vast majority of cases occur in those below the age of 18. It is commonly described as one of the “small, round, blue cell tumours of childhood” due to its appearance on an H&E stain. Despite being a relatively rare cancer, it accounts for approximately 40% of all recorded soft tissue sarcomas. RMS can occur in any site on the body, but is primarily found in the head, neck, orbit, genitourinary tract, genitals, and extremities. There are no clear risk factors for RMS, but the disease has been associated with some congenital abnormalities. Signs and symptoms vary according to tumor site, and prognosis is closely tied to the location of the primary tumor. Common site of metastasis include the lungs, bone marrow, and bones. There are many classification systems for RMS and a variety of defined histological types. Embryonal rhabdomyosarcoma is the most common type and comprises about 60% of cases. Patient outcomes vary considerably, with 5 years survival rates between 35% and 95% depending on the type of RMS involved, so clear diagnosis is critical for effective treatment and management. Unfortunately, accurate and quick diagnosis is often difficult due to the heterogeneity of RMS tumors and a lack of strong genetic markers of the disease. Treatment usually involves a combination of surgery, chemotherapy, and radiation. Sixty percent to 70% of newly diagnosed patients with nonmetastatic disease can be cured using this combined approach to therapy. Despite aggressive multimodality treatment, less than 20% of patients with metastatic RMS are able to be cured of their disease.

RMS on Wikipedia

Random information on the term “BRS”:

Railroad Development Corporation is an American railroad holding company based in Pittsburgh, Pennsylvania. RDC operates several short line railroads outside the United States and acts as an investor, with management and institutional investors as partners.

Henry Posner III is a founding principal of the company.

RDC participates in the ownership of two rail lines in Argentina:

Managed the previously closed 914 mm (3 ft) gauge Ferrovias Guatemala (FVG) under a 50-year concession from 1997. In August 2006, the government of Guatemala invalidated a 2003 contract for the usufruct of rolling stock and other equipment. Due to the continuing uncertainty leading to losses, FVG decided to suspend all operations as of October 1, 2007 while continuing with legal actions against the Guatemalan government.

In July 1999 the Peruvian government awarded a consortium led by RDC a 30-year concession to operate the former Ferrocarril del Centro. Investors in Ferrocarril Central Andino (FCCA) include RDC, Juan Olaechea & Company, Minas Buenaventura, ADR Inversiones, and Inversiones Andino. It was agreed in June 2006 by the Peruvian government that FCCA should go ahead with converting the Ferrocarril Huancayo – Huancavelica from 3 ft (914 mm) to 4 ft 8 1⁄2 in (1,435 mm) (standard gauge). Estimated to take 16 months, the US$33m project was to be funded jointly by the government and the Development Bank of Latin America.

BRS on Wikipedia

Random information on the term “EIK”:

Nina Eik-Nes, née Nina Lange Dahler (5 January 1900 – 22 May 1997) was a Norwegian politician for the Liberal Party.

She served as a deputy representative to the Norwegian Parliament from Nord-Trøndelag during the terms 1945–1949 and 1950–1953. She lived in Sparbu at the time. She was a prominent member of the Norwegian Women’s Public Health Association, especially during World War II. Among others, she helped set up a field hospital at Mære School of Agriculture during the Norwegian Campaign. The field hospital was not used as such, but the equipment was stored, secretly kept away from German occupying forces by Eik-Nes and portioned out later. The work of Eik-Nes and her organization became especially important in 1944, when the liberation of Northern Norway and the Wehrmacht’s subsequent scorched earth tactic meant that thousands of people fled south, needing help from the Women’s Public Health Association.

She was married to priest and cultural worker Knut Eik-Nes (1900–1997), and was the mother of hormone researcher Kristen Dahler Eik-Nes. Through her daughter Eli, born 1921, she was a mother-in-law of Magne Oftedal.

EIK on Wikipedia