This time we are looking on the crossword clue for: Big time.
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Possible Answers: AGE, ERA, EON, MAJORLEAGUE.
Random information on the term “AGE”:
Ageing or aging (see spelling differences), is the process of becoming older. The term refers especially to human beings, many animals, and fungi, whereas for example bacteria, perennial plants and some simple animals are potentially immortal. In the broader sense, ageing can refer to single cells within an organism which have ceased dividing (cellular senescence) or to the population of a species (population ageing).
In humans, ageing represents the accumulation of changes in a human being over time, encompassing physical, psychological, and social changes. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Ageing is among the greatest known risk factors for most human diseases: of the roughly 150,000 people who die each day across the globe, about two thirds die from age-related causes.
The causes of ageing are uncertain; current theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby internal processes (such as DNA methylation) may cause ageing. Programmed ageing should not be confused with programmed cell death (apoptosis).
Random information on the term “ERA”:
In baseball statistics, earned run average (ERA) is the mean of earned runs given up by a pitcher per nine innings pitched (i.e. the traditional length of a game). It is determined by dividing the number of earned runs allowed by the number of innings pitched and multiplying by nine. Runs resulting from defensive errors (including pitchers’ defensive errors) are recorded as unearned runs and omitted from ERA calculations.
Henry Chadwick is credited with devising the statistic, which caught on as a measure of pitching effectiveness after relief pitching came into vogue in the 1900s. Prior to 1900 – and, in fact, for many years afterward – pitchers were routinely expected to pitch a complete game, and their win-loss record was considered sufficient in determining their effectiveness.
After pitchers like James Otis Crandall and Charley Hall made names for themselves as relief specialists, gauging a pitcher’s effectiveness became more difficult using the traditional method of tabulating wins and losses. Some criterion was needed to capture the apportionment of earned-run responsibility for a pitcher in games that saw contributions from other pitchers for the same team. Since pitchers have primary responsibility to put opposing batters out, they must assume responsibility when a batter they do not retire at the plate moves to base, and eventually reaches home, scoring a run. A pitcher is assessed an earned run for each run scored by a batter (or that batter’s pinch-runner) who reaches base while batting against that pitcher. The National League first tabulated official earned run average statistics in 1912 (the outcome was called “Heydler’s statistic” for a while, after then-NL secretary John Heydler), and the American League later accepted this standard and began compiling ERA statistics.
Random information on the term “EON”:
The geologic time scale (GTS) is a system of chronological dating that relates geological strata (stratigraphy) to time, and is used by geologists, paleontologists, and other Earth scientists to describe the timing and relationships of events that have occurred during Earth’s history. The table of geologic time spans, presented here, agrees with the nomenclature, dates and standard color codes set forth by the International Commission on Stratigraphy.
Evidence from radiometric dating indicates that Earth is about 4.54 billion years old. The geology or deep time of Earth’s past has been organized into various units according to events which took place in each period. Different spans of time on the GTS are usually marked by changes in the composition of strata which correspond to those, and indicate major geological or paleontological events, such as mass extinctions. For example, the boundary between the Cretaceous period and the Paleogene period is defined by the Cretaceous–Paleogene extinction event, which marked the demise of the non-avian dinosaurs and many other groups of life. Older time spans, which predate the reliable fossil record (before the Proterozoic eon), are defined by their absolute age.