Blazing Saddles director Brooks

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Possible Answers:

Mel.

Last seen on: Daily Celebrity Crossword – 5/15/19 Wayback Wednesday

Random information on the term “Mel”:

The mouse erythroleukemia cell line F4N (MEL) is a mouse-derived aneuploid cell line. It was established in 1977. Eight percent of the total number of cells in culture undergo spontaneous apoptosis.

Mel on Wikipedia