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Possible Answers:
DCC.
Last seen on: Newsday.com Crossword – Jun 18 2022s
Random information on the term “DCC”:
2ED7, 2ED8, 2ED9, 2EDB, 2EDD, 2EDE, 3AU4, 4URT
1630
13176
ENSG00000187323
ENSMUSG00000060534
P43146
P70211
NM_005215
NM_007831
NP_005206
NP_031857
Netrin receptor DCC, also known as DCC, or colorectal cancer suppressor is a protein which in humans is encoded by the DCC gene. DCC has long been implicated in colorectal cancer and its previous name was Deleted in colorectal carcinoma. Netrin receptor DCC is a single transmembrane receptor.
Since it was first discovered in a colorectal cancer study in 1990, DCC has been the focus of a significant amount of research. DCC held a controversial place as a tumour suppressor gene for many years, and is well known as an axon guidance receptor that responds to netrin-1.
More recently DCC has been characterized as a dependence receptor, and many hypotheses have been put forward that have revived interest in DCC’s candidacy as a tumour suppressor gene, as it may be a ligand-dependent suppressor that is frequently epigenetically silenced.