Difficult burden

This time we are looking on the crossword clue for: Difficult burden.
it’s A 16 letters crossword puzzle definition. See the possibilities below.

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Possible Answers: ONUS, CROSS.

Last seen on: –Newsday.com Crossword – Aug 31 2021
Wall Street Journal Crossword – Sep 17 2018 – Where the Wild Things Are
-Universal Crossword – May 22 2018