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Possible Answers: ASS, SAP, OAF, NERD, IDIOT, LOON, YOYO, CLOD, LOUT, TWIT, GOOSE, FOOL, BOZO, SCHMO, BOOB, MORON, JERK, SIMP, NINNY, NITWIT, AIRHEAD, CHUMP, LUNK, PINHEAD, BIRDBRAIN, SCHNOOK, FATHEAD, H, DULLARD, IMBECILE, HALFWIT, MUTTONHEAD, CHOWDERHEAD, SAPHEAD, DUMMKOPF, CABBAGEHEAD.
Last seen on: –L.A. Times Daily Crossword – Jul 31 2022
–Newsday.com Crossword – Apr 7 2022s
–L.A. Times Daily Crossword – Feb 22 2022
–NY Times Crossword 26 Feb 21, Friday
–Universal Crossword – Feb 24 2019
–The Washington Post Crossword – Nov 10 2018
–LA Times Crossword 10 Nov 18, Saturday
Random information on the term “ASS”:
The donkey or ass (Equus africanus asinus) is a domesticated member of the horse family, Equidae. The wild ancestor of the donkey is the African wild ass, E. africanus. The donkey has been used as a working animal for at least 5000 years. There are more than 40 million donkeys in the world, mostly in underdeveloped countries, where they are used principally as draught or pack animals. Working donkeys are often associated with those living at or below subsistence levels. Small numbers of donkeys are kept for breeding or as pets in developed countries.
A male donkey or ass is called a jack, a female a jenny or jennet; a young donkey is a foal. Jack donkeys are often used to mate with female horses to produce mules; the biological “reciprocal” of a mule, from a stallion and jenny as its parents instead, is called a hinny.
Asses were first domesticated around 3000 BC, probably in Egypt or Mesopotamia, and have spread around the world. They continue to fill important roles in many places today. While domesticated species are increasing in numbers, the African wild ass is an endangered species. As beasts of burden and companions, asses and donkeys have worked together with humans for millennia.
Random information on the term “SAP”:
4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV
325
20219
ENSG00000132703
ENSMUSG00000026542
P02743
P12246
NM_001639
NM_011318
NP_001630
NP_035448.2
NP_035448
The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called “amyloid”. APCS is its human gene.
AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1-[6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl] pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP.
Random information on the term “OAF”:
In human–computer interaction, computer accessibility (also known as accessible computing) refers to the accessibility of a computer system to all people, regardless of disability type or severity of impairment. The term “accessibility” is most often used in reference to specialized hardware or software, or a combination of both, designed to enable use of a computer by a person with a disability or impairment. Specific technologies may be referred to as assistive technology.
There are many disabilities or impairments that can be a barrier to effective computer use. These impairments, which can be acquired from disease, trauma, or may be congenital, include but are not limited to:
Accessibility is often abbreviated as the numeronym a11y, where the number 11 refers to the number of letters omitted. This parallels the abbreviations of internationalization and localization as i18n and l10n respectively.
People wishing to overcome an impairment in order to use a computer comfortably and productively may require a “special needs assessment” by an assistive technology consultant (such as an occupational therapist, a rehabilitation engineering technologist, or an educational technologist) to help them identify and configure appropriate assistive technologies to meet individual needs. Even those who are unable to leave their own home or who live far from assessment providers may be assessed (and assisted) remotely using remote desktop software and a web cam. For example, the assessor logs on to the client’s computer via a broadband Internet connection, observes the users computer skills, and then remotely makes accessibility adjustments to the client’s computer where necessary.
Random information on the term “NERD”:
N*E*R*D (a backronym of No-one Ever Really Dies) is an American funk rock band. Pharrell Williams and Chad Hugo were signed by Teddy Riley to Virgin Records as a duo, The Neptunes. After producing songs for several artists throughout the late 1990s and early 2000s, the production duo formed the band with Sarah Atyat Williams as a side project of The Neptunes in 1999. N*E*R*D’s debut album, In Search Of…, sold 603,000 copies in the United States and was certified Gold by the Recording Industry Association of America (RIAA). It was also awarded the second annual Shortlist Music Prize. The band’s second album, Fly or Die, sold 412,000 copies in the United States, but shipped at least 500,000 units, certifying it Gold.
In 2005, N*E*R*D ended their contract with Virgin and disbanded. Three years later, the band reunited under Star Trak Entertainment, a subsidiary of Interscope Records established by Williams and Hugo. The band’s third album, Seeing Sounds, released in 2008, sold just under 80,000 copies in its first week. The album was followed by Nothing, which was released in 2010.
Random information on the term “YOYO”:
The 2013 World Yo-Yo Contest was the culminating yo-yo competition of the worldwide competitive circuit. The winners from this competition in any of the six championship divisions were deemed the current World Yo-Yo Champion until the 2014 World Champions were crowned. The competition was run by Gregory Cohen injunction with the International Yo-Yo Federation (IYYF). The competition took place at the Rozen Plaza Hotel in Orlando, Florida, USA from August 8–10, 2013.
The first World Yo-Yo Contest was held in London, England, in 1932. The winner was Harvey Lowe. However, the contest was not held annually until 1992, when Dale Oliver started one in Montreal, Canada during that year’s annual International Jugglers’ Association’s (IJA) convention. The contest was held during this convention until 1999, when it was held in Hawaii. The 2000 contest was held at Universal Studios in Orlando, but in 2001, the event moved to the Rosen Plaza Hotel, where it was held annually until 2013 by Gregory Cohen, owner and operator of YoYoGuy and Infinite Illusions. After the 2013 contest, an international coalition (the IYYF) was formed to organize a new, rotating contest which will be held in a different venue/country every year.
Random information on the term “CLOD”:
The beef clod or shoulder is one of the cheapest cuts of beef and is taken from the shoulder region of the cattle. This is why it is sometimes called chuck or shoulder clod, because obviously “chuck” or “clod” means cheap, apparently. Beef clod consists of a large muscle system and some fat that covers the muscles. Beef clod can be prepared in a variety of methods both dry and moist, but the most recommended method to cook beef clod is to cook it with moist heat or braising. Long slow smoking also provides acceptable results.
Random information on the term “TWIT”:
Coordinates: 38°16′35″N 122°40′03″W / 38.2764301°N 122.6676119°W / 38.2764301; -122.6676119
TWiT.tv, which is the operating trade name of TWiT LLC, is a podcast (although TWiT uses the term “netcast”) network founded by technology broadcaster and author Leo Laporte and run by his wife and company CEO Lisa Laporte. The network began operation in April 2005 with the launch of This Week in Tech. Security Now was the second podcast on the network, debuting in August of that year. Currently, the network hosts twenty-two podcasts and live streaming shows, including The Tech Guy, This Week in Tech, Security Now, FLOSS Weekly, MacBreak Weekly, Tech News Today, Tech News 2Night, and 15 other podcasts covering various topics including technology companies, computer security, social networking, and current technology news.
TWiT founder and owner Laporte, in an October 2009 speech, stated that it grossed revenues of $1.5 million per year, while costs were around $350,000. In November 2014, American Public Media’s Marketplace reported that TWiT makes $6 million in ad revenue a year from 5 million TWiT podcasts downloaded each month, mostly in the form of audio, and that 3,000 to 4,000 people watch its live-streamed shows. On March 18, 2015, prior to the filming of This Week in Google, Leo Laporte stated that TWiT expects to make $7 million in revenue in fiscal year 2015.
Random information on the term “GOOSE”:
IEC 61850 is a standard for vendor-agnostic engineering of the configuration of Intelligent Electronic Devices for electrical substation automation systems to be able to communicate with each other. IEC 61850 is a part of the International Electrotechnical Commission’s (IEC) Technical Committee 57 (TC57) reference architecture for electric power systems. The abstract data models defined in IEC 61850 can be mapped to a number of protocols. Current mappings in the standard are to MMS (Manufacturing Message Specification), GOOSE (Generic Object Oriented Substation Event), SMV (Sampled Measured Values),[clarification needed] and soon to Web Services. These protocols can run over TCP/IP networks or substation LANs using high speed switched Ethernet to obtain the necessary response times below four milliseconds for protective relaying.
Multiple protocols exist for substation automation, which include many proprietary protocols with custom communication links. Interoperation of devices from different vendors would be an advantage to users of substation automation devices. An IEC project group of about 60 members from different countries worked in three IEC working groups from 1995. They responded to all the concerns and objectives and created IEC 61850. The objectives set for the standard were:
Random information on the term “FOOL”:
Nationale Regionale Transport is a domestic airline based in Libreville, Gabon. Its main base is Libreville International Airport. It was rebranded in 2009 from National Airways Gabon.
The airline is on the list of air carriers banned in the European Union.
The Nationale Regionale Transport fleet includes the following aircraft (as of February 2014):
Nationale Regionale Transport has also operated the following aircraft:
Random information on the term “SIMP”:
Weakly interacting massive particles (WIMPs) are hypothetical particles that are thought to constitute dark matter. There exists no clear definition of a WIMP, but broadly a WIMP is a new elementary particle which interacts via gravity and any other force (or forces), potentially not part of the standard model itself, which is as weak as or weaker than the weak nuclear force, but also non-vanishing in its strength. A WIMP must also have been produced thermally in the early Universe, similarly to the particles of the standard model according to Big Bang cosmology, and usually will constitute cold dark matter. Obtaining the correct abundance of dark matter today via thermal production requires a self-annihilation cross section of
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σ
v
⟩
≃
3
×
10
−
26
c
m
3
s
−
1
{\displaystyle \langle \sigma v\rangle \simeq 3\times 10^{-26}\mathrm {cm} ^{3}\;\mathrm {s} ^{-1}}
, which is roughly what is expected for a new particle in the 100 GeV mass range that interacts via the electroweak force. Because supersymmetric extensions of the standard model of particle physics readily predict a new particle with these properties, this apparent coincidence is known as the “WIMP miracle”, and a stable supersymmetric partner has long been a prime WIMP candidate. However, recent null results from direct detection experiments including LUX and SuperCDMS, along with the failure to produce evidence of supersymmetry in the Large Hadron Collider (LHC) experiment has cast doubt on the simplest WIMP hypothesis. Experimental efforts to detect WIMPs include the search for products of WIMP annihilation, including gamma rays, neutrinos and cosmic rays in nearby galaxies and galaxy clusters; direct detection experiments designed to measure the collision of WIMPs with nuclei in the laboratory, as well as attempts to directly produce WIMPs in colliders, such as the LHC.
Random information on the term “H”:
The International Phonetic Alphabet (IPA) is an alphabetic system of phonetic notation based primarily on the Latin alphabet. It was devised by the International Phonetic Association in the late 19th century as a standardized representation of the sounds of spoken language. The IPA is used by lexicographers, foreign language students and teachers, linguists, speech-language pathologists, singers, actors, constructed language creators and translators.
The IPA is designed to represent only those qualities of speech that are part of oral language: phones, phonemes, intonation and the separation of words and syllables. To represent additional qualities of speech, such as tooth gnashing, lisping, and sounds made with a cleft lip and cleft palate, an extended set of symbols, the extensions to the International Phonetic Alphabet, may be used.
IPA symbols are composed of one or more elements of two basic types, letters and diacritics. For example, the sound of the English letter ⟨t⟩ may be transcribed in IPA with a single letter, [t], or with a letter plus diacritics, [t̺ʰ], depending on how precise one wishes to be.[note 1] Often, slashes are used to signal broad or phonemic transcription; thus, /t/ is less specific than, and could refer to, either [t̺ʰ] or [t], depending on the context and language.