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Possible Answers: ILL, SAP, INFO, IDIOT, DIRT, TWIT, SCHMO, FACTS, BOOB, DRUG, GRASS, PHAT, POOP, STUPE, SIMP, NITWIT, SKINNY, DINGBAT, PINHEAD, SCHNOOK, DINGALING, IMBECILE, SHNOOK, NUMBSKULL.
Last seen on: –Wall Street Journal Crossword – April 06 2022 – This Puzzle’s Title Contains Six Words
–NY Times Crossword 18 Feb 22, Friday
–NY Times Crossword 17 Apr 20, Friday
–NY Times Crossword 2 Apr 20, Thursday
–LA Times Crossword 3 Nov 19, Sunday
–Wall Street Journal Crossword – July 19 2019 – The Paper Chase
–New York Times Crossword – Mar 10 2019
–Thomas Joseph – King Feature Syndicate Crossword – Dec 20 2018
–NY Times Crossword 29 Sep 18, Saturday
–NY Times Crossword 29 Jun 2018, Friday
-The Telegraph – Cryptic Crossword – November 24 2017
-The Telegraph – Cryptic Crossword – November 24 2017
Random information on the term “ILL”:
Illorsuit Heliport (IATA: IOT, ICAO: BGLL) is a heliport in Illorsuit, a village on an island of the same name in the Qaasuitsup municipality in western Greenland. The heliport is considered a helistop, and is served by Air Greenland as part of government contract.
Air Greenland operates government contract flights to villages in the Uummannaq Fjord region. These mostly cargo flights are not featured in the timetable, although they can be pre-booked. Departure times for these flights as specified during booking are by definition approximate, with the settlement service optimized on the fly depending on local demand for a given day.
Random information on the term “SAP”:
4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV
325
20219
ENSG00000132703
ENSMUSG00000026542
P02743
P12246
NM_001639
NM_011318
NP_001630
NP_035448.2
NP_035448
The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called “amyloid”. APCS is its human gene.
AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1-[6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl] pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP.
Random information on the term “INFO”:
Robert Todd Carroll (May 18, 1945 – August 25, 2016) was an American writer and academic. Carroll is best known for his contributions in the field of skepticism; he achieved notability by publishing The Skeptic’s Dictionary online in 1994. He was elected a fellow of the Committee for Skeptical Inquiry in 2010. He described himself as a naturalist, an atheist, a materialist, a metaphysical libertarian, and a positivist.
His published books include Becoming a Critical Thinker; The Skeptic’s Dictionary; The Skeptic’s Dictionary for Kids; The Critical Thinker’s Dictionary; Unnatural Acts: Critical Thinking, Skepticism, and Science Exposed!; The Commonsense Philosophy of Religion of Edward Stillingfleet; Student Success Guide: Writing Skills and Student Success Guide: Reading Skills.
He was a professor of philosophy at Sacramento City College from 1977 until his retirement in 2007.
Carroll was born in Joliet, Illinois on May 18, 1945. His father worked in a coal processing plant. The family moved to San Diego in 1954 where Carroll grew up. He describes his early years in Ocean Beach as an ideal childhood. He was raised Catholic.
Random information on the term “DIRT”:
Soil is a mixture of minerals, organic matter, gases, liquids, and countless organisms that together support life on Earth. Soil is a natural body called the pedosphere which has four important functions: it is a medium for plant growth; it is a means of water storage, supply and purification; it is a modifier of Earth’s atmosphere; it is a habitat for organisms; all of which, in turn, modify the soil.
Soil is called the Skin of the Earth and interfaces with the lithosphere, the hydrosphere, the atmosphere, and the biosphere. The term pedolith, used commonly to refer to the soil, literally translates ground stone. Soil consists of a solid phase of minerals (the soil matrix) and organic matter, as well as a porous phase that holds gases (the soil atmosphere) and water (the soil solution). Accordingly, soils are often treated as a three-state system of solids, liquids, and gases.
Soil is a product of the influence of climate, relief (elevation, orientation, and slope of terrain), organisms, and its parent materials (original minerals) interacting over time. Soil continually undergoes development by way of numerous physical, chemical and biological processes, which include weathering with associated erosion. Given its complexity and strong internal connectedness soil has been considered as an ecosystem by soil ecologists.
Random information on the term “TWIT”:
Coordinates: 38°16′35″N 122°40′03″W / 38.2764301°N 122.6676119°W / 38.2764301; -122.6676119
TWiT.tv, which is the operating trade name of TWiT LLC, is a podcast (although TWiT uses the term “netcast”) network founded by technology broadcaster and author Leo Laporte and run by his wife and company CEO Lisa Laporte. The network began operation in April 2005 with the launch of This Week in Tech. Security Now was the second podcast on the network, debuting in August of that year. Currently, the network hosts twenty-two podcasts and live streaming shows, including The Tech Guy, This Week in Tech, Security Now, FLOSS Weekly, MacBreak Weekly, Tech News Today, Tech News 2Night, and 15 other podcasts covering various topics including technology companies, computer security, social networking, and current technology news.
TWiT founder and owner Laporte, in an October 2009 speech, stated that it grossed revenues of $1.5 million per year, while costs were around $350,000. In November 2014, American Public Media’s Marketplace reported that TWiT makes $6 million in ad revenue a year from 5 million TWiT podcasts downloaded each month, mostly in the form of audio, and that 3,000 to 4,000 people watch its live-streamed shows. On March 18, 2015, prior to the filming of This Week in Google, Leo Laporte stated that TWiT expects to make $7 million in revenue in fiscal year 2015.
Random information on the term “FACTS”:
In contemporary philosophy, a brute fact is a fact that has no explanation. More narrowly, brute facts may instead be defined as those facts which cannot be explained (as opposed to simply having no explanation). To reject the existence of brute facts is to think that everything can be explained. (“Everything can be explained” is sometimes called the principle of sufficient reason). There are two ways to explain something: say what “brought it about”, or describe it at a more “fundamental” level.[citation needed] For example, a cat displayed on a computer screen can be explained, more “fundamentally”, as there being certain voltages in bits of metal in my screen, which in turn can be explained, more “fundamentally”, as that there are certain subatomic particles moving in a certain way. If we keep explaining the world in this way and reach a point at which no more “deeper” explanations can be given, then we would have found some facts which are brute or inexplicable, in the sense that we cannot give them an ontological explanation[citation needed]. As it might be put, there may exist some things that just are. The same thing can be done with causal explanations. If nothing made the big bang expand at the velocity it did, then this is a brute fact in the sense that it lacks a causal explanation.
Random information on the term “DRUG”:
In medicine, a bolus (from Latin bolus, ball) is the administration of a discrete amount of medication, drug or other compound in order to raise its concentration in blood to an effective level. The administration can be given by injection: intravenously, intramuscularly, intrathecally, subcutaneously, and by inhalation. The article on routes of administration provides more information, as the preceding list of ROIs is not exhaustive.
The placement of the bolus dose depends on the systemic levels of the contents desired throughout the body. An intramuscular injection of vaccines allows for a slow release of the antigen to stimulate the body’s immune system and to allow time for developing antibodies. Subcutaneous injections are used by heroin addicts (called ‘skin popping’, referring to the bump formed by the bolus of heroin), to sustain a slow release that staves off withdrawal symptoms without producing euphoria.
A bolus delivered directly to the veins through an intravenous drip allows a much faster delivery which quickly raises the concentration of the substance in the blood to an effective level. This is typically done at the beginning of a treatment or after a removal of medicine from blood (e.g. through dialysis).
Random information on the term “GRASS”:
An object-based spatial database is a spatial database that stores the location as objects. The object-based spatial model treats the world as surface littered with recognizable objects (e.g. cities, rivers), which exist independent of their locations.
Objects can be simple as polygons and lines, or be more complex to represent cities.
While a field-based data model sees the world as a continuous surface over which features (e.g. elevation) vary, using an object-based spatial database, it is easier to store additional attributes with the objects, such as direction, speed, etc. Using these attributes can make it easier to answer queries like “find all tanks whose speed is 10 km and oriented to north”. Or “find all enemy tanks in a certain region”.
Storing attributes with objects can provide better result presentation and improved manipulation capabilities in a more efficient way. In a field-based data model, this information is usually stored at different layers and it is harder to extract different information from various layers. This data model can be applied above the ER as in GERM model and GISER.
Random information on the term “POOP”:
Feces or faeces (British and Latin) are the solid or semisolid metabolic waste from an animal’s digestive tract, discharged through the anus or cloaca during a process called defecation. Urine and feces together are called excreta.
Collected feces has various uses, namely as fertilizer or soil conditioner in agriculture, as a fuel source, or for medicinal purposes (fecal transplants or fecal bacteriotherapy, in the case of human feces).
After an animal has digested eaten material, the remains of that material are discharged from its body as waste. Although it is lower in energy than the food from which it is derived, feces may retain a large amount of energy, often 50% of that of the original food. This means that of all food eaten, a significant amount of energy remains for the decomposers of ecosystems. Many organisms feed on feces, from bacteria to fungi to insects such as dung beetles, who can sense odors from long distances. Some may specialize in feces, while others may eat other foods as well. Feces serve not only as a basic food, but also as a supplement to the usual diet of some animals. This is known as coprophagia, and occurs in various animal species such as young elephants eating the feces of their mothers in order to gain essential gut flora, or by other animals such as dogs, rabbits, and monkeys.
Random information on the term “SIMP”:
Weakly interacting massive particles (WIMPs) are hypothetical particles that are thought to constitute dark matter. There exists no clear definition of a WIMP, but broadly a WIMP is a new elementary particle which interacts via gravity and any other force (or forces), potentially not part of the standard model itself, which is as weak as or weaker than the weak nuclear force, but also non-vanishing in its strength. A WIMP must also have been produced thermally in the early Universe, similarly to the particles of the standard model according to Big Bang cosmology, and usually will constitute cold dark matter. Obtaining the correct abundance of dark matter today via thermal production requires a self-annihilation cross section of
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σ
v
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3
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10
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26
c
m
3
s
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1
{\displaystyle \langle \sigma v\rangle \simeq 3\times 10^{-26}\mathrm {cm} ^{3}\;\mathrm {s} ^{-1}}
, which is roughly what is expected for a new particle in the 100 GeV mass range that interacts via the electroweak force. Because supersymmetric extensions of the standard model of particle physics readily predict a new particle with these properties, this apparent coincidence is known as the “WIMP miracle”, and a stable supersymmetric partner has long been a prime WIMP candidate. However, recent null results from direct detection experiments including LUX and SuperCDMS, along with the failure to produce evidence of supersymmetry in the Large Hadron Collider (LHC) experiment has cast doubt on the simplest WIMP hypothesis. Experimental efforts to detect WIMPs include the search for products of WIMP annihilation, including gamma rays, neutrinos and cosmic rays in nearby galaxies and galaxy clusters; direct detection experiments designed to measure the collision of WIMPs with nuclei in the laboratory, as well as attempts to directly produce WIMPs in colliders, such as the LHC.