Down or blue

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SAD.

Last seen on: LA Times Crossword 11 Dec 18, Tuesday

Random information on the term “SAD”:

Sagittal abdominal diameter (SAD) is a measure of visceral obesity, the amount of fat in the gut region. SAD is the distance from the small of the back to the upper abdomen. SAD may be measured when standing[1] or supine.[2] SAD may be measured at any point from the narrowest point between the last rib and the iliac crests to the midpoint of the iliac crests.[1][2][3]

SAD is a strong predictor of coronary disease, with higher values indicating increased risk independent of BMI.[1]

For persons of normal BMI, SAD should be under 25 centimetres (9.8 in). The amount this measure exceeds 30 centimetres (12 in) correlates to increased cardiovascular risk and insulin resistance.[2] SAD measure of men in their 40s, greater than 25 cm, also predicts significantly higher risk of Alzheimer’s disease 30 years later.[4] An article in Annals of Neurology links visceral fat to lower brain volume.[5]

SAD on Wikipedia