This time we are looking on the crossword clue for: Eng. course.
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Possible Answers: LIT, COMP.
Last seen on: –Premier Sunday – King Feature Syndicate Crossword – Aug 14 2022s
Random information on the term “LIT”:
Lit Brothers was a moderately-priced department store based in Philadelphia. Samuel and Jacob Lit opened the first store at North 8th and Market Streets in 1891. Lit’s positioned itself well as a more affordable alternate to competitors Strawbridge and Clothier, Wanamaker’s, and Gimbels. The store’s slogan was “A Great Store in A Great City,” and it was noted for its millinery department.
The Lit Brother Store building was added to the National Register of Historic Places in 1979, and is located in the East Center City Commercial Historic District.
In 1891, Rachel P. Lit (1858-1919, later surnamed Weddel, still later Arnold) opened a woman’s clothing shop on the corner of Market and N. 8th Streets. With the administration and innovative advertising techniques of her brothers, Colonel Samuel David Lit (1859-1929) and Jacob David Lit (1872-1950), their small store soon became one of the largest retail stores in Philadelphia. From 1895 to 1907, the store continued to expand, with the company taking over the remaining buildings on the block of Market between North 7th and 8th Streets – including the J. M. Maris Dry Goods Store, the Bailey Store and the J. B. Lippincott & Co. Building – and adding new buildings at either end of the block designed to blend in with the existing buildings. With alterations and additions, the Lit Brothers Store became the only full block of Victorian architecture in Philadelphia, composed of 33 buildings constructed between 1859 and 1918, with a common interior. The new buildings and the alterations were designed by Charles M. Autenrieth and Edward Collins.
Random information on the term “COMP”:
3FBY
1311
12845
ENSG00000105664
ENSMUSG00000031849
P49747
Q9R0G6
NM_000095
NM_016685
NP_000086
NP_057894.2
NP_057894
Cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5, is an extracellular matrix (ECM) protein primarily present in cartilage. In humans it is encoded by the COMP gene.
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfide bonds. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
COMP is a marker of cartilage turnover. It is present in high quantities in fibrotic scars and systemic sclerosis, and it appears to have a role in vascular wall remodeling.