Fall guy

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Possible Answers: ADAM, SAP, TOOL, GOAT, PATSY, DUPE, STOOGE, MARK, CHUMP, SCAPEGOAT, SACRIFICIALLAMB.

Last seen on: –Thomas Joseph – King Feature Syndicate Crossword – Apr 17 2021
Thomas Joseph – King Feature Syndicate Crossword – Jan 20 2021
Eugene Sheffer – King Feature Syndicate Crossword – Dec 24 2020
Eugene Sheffer – King Feature Syndicate Crossword – Dec 2 2020
Eugene Sheffer – King Feature Syndicate Crossword – Mar 23 2020
The Sun – Two Speed Crossword – Jul 31 2019

Random information on the term “ADAM”:

According to the Book of Jubilees, Awan (also Avan or Aven, from Heb. אָוֶן aven – “vice”, “iniquity”, “potency”) was the wife and sister of Cain and the daughter of Adam and Eve. Similarly, her sister Azura (עֲצֻרָה atzurah – “restraint”) was the wife of Cain’s two brothers – Abel and after Abel’s murder, Seth.

ADAM on Wikipedia

Random information on the term “SAP”:

4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV

325

20219

ENSG00000132703

ENSMUSG00000026542

P02743

P12246

NM_001639

NM_011318

NP_001630

NP_035448.2
NP_035448

The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called “amyloid”. APCS is its human gene.


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AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1-[6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl] pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP.

SAP on Wikipedia

Random information on the term “TOOL”:

Tool is an American rock band from Los Angeles, California. Formed in 1990, the group’s line-up includes drummer Danny Carey, guitarist Adam Jones, and vocalist Maynard James Keenan. Justin Chancellor has been the band’s bassist since 1995, replacing their original bassist Paul D’Amour. Tool has won three Grammy Awards, performed worldwide tours, and produced albums topping the charts in several countries.

The band emerged with a heavy metal sound on their first studio album, Undertow (1993), and later became a dominant act in the alternative metal movement, with the release of their second album, Ænima in 1996. Their efforts to unify musical experimentation, visual arts, and a message of personal evolution continued, with Lateralus (2001) and the most recent album, 10,000 Days (2006), gaining the band critical acclaim, and commercial success around the world.

Due to Tool’s incorporation of visual arts and very long and complex releases, the band is generally described as a style-transcending act and part of progressive rock, psychedelic rock, and art rock. The relationship between the band and today’s music industry is ambivalent, at times marked by censorship, and the band’s insistence on privacy.

TOOL on Wikipedia

Random information on the term “GOAT”:

See text.

Capra is a genus of mammals, the goats or wild goats, composed of up to nine species, including the wild goat, the markhor, and several species known as ibex. The domestic goat (Capra aegagrus hircus) is a domesticated subspecies of the wild goat (Capra aegagrus). Evidence of goat domestication dates back more than 8,500 years.

Wild goats are animals of mountain habitats. They are very agile and hardy, able to climb on bare rock and survive on sparse vegetation. They can be distinguished from the genus Ovis, which includes sheep, by the presence of scent glands close to the feet, in the groin, and in front of the eyes, and the absence of other facial glands, and by the presence of a beard in the males, and of hairless calluses on the knees of the forelegs.

The Rocky Mountain goat is in a separate genus, Oreamnos.

All members of the Capra genus are bovids (members of the family Bovidae), and more specifically caprids (subfamily Caprinae). As such they are ruminants, meaning they chew the cud, and have four-chambered stomachs which play a vital role in digesting, regurgitating, and redigesting their food.

GOAT on Wikipedia