Family member

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Possible Answers: COUSIN, SON, SIS, PAPA, DAD, MAMA, AUNT, NIECE, MOM, UNCLE, INLAW, SIB, QUAD, SISTER, PARENT, CHILD, MAMMA, STEPSON, FATHER, NEPHEW, SONINLAW, AUNTY, MOBSTER, GRANDMA, GRANDPA, MAFIOSO, GRANDSON, GRAMPA, GRANNIE, STEPMOTHER, GRANDDAD, GRANDMAMA.

Last seen on: –USA Today Crossword – Apr 20 2020
USA Today Crossword – Apr 2 2020
USA Today Crossword – Mar 16 2020
The Washington Post Crossword – Oct 7 2018
LA Times Crossword 7 Oct 18, Sunday
The Washington Post Crossword – August 9 2018
LA Times Crossword 9 Aug 2018, Thursday

Random information on the term “SON”:

6651

20658

ENSG00000159140

ENSMUSG00000022961

P18583

Q9QX47

NM_138927

NM_019973
NM_178880

NP_001278340
NP_001278341
NP_115571
NP_620305

NP_849211.3
NP_064357
NP_849211

SON protein is a protein that in humans is encoded by the SON gene.

SON is the name that has been given to a large Ser/Arg (SR)-related protein, which is a splicing co-factor that contributes to an efficient splicing within cell cycle progression. It is also known as BASS1 (Bax antagonist selected in saccharomyces 1) or NRE-binding protein (Negative regulatory element-binding protein). The most common gene name of this splicing protein- which is only found in Humans (Homo sapiens)- is SON, but C21orf50, DBP5, KIAA1019 and NREBP can also be used as synonyms.

The protein encoded by SON gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing.

SON on Wikipedia

Random information on the term “SIS”:

Michael James Sis (born January 9, 1960) is a Catholic bishop in the United States. He is the sixth bishop of the Diocese of San Angelo in the state of Texas.

Michael James Sis was born in Mt. Holly, New Jersey. He was the fourth of five children born to Raymond and Janice Sis. Sis grew up in Bryan, Texas where he attended St. Joseph School and the Bryan Independent School District. He earned a bachelor of arts degree in philosophy from the University of Notre Dame, a bachelor’s degree in theology from the Gregorian University in Rome and a licentiate in moral theology from the Alphonsian Academy in Rome. Sis was ordained a priest for the Diocese of Austin on July 19, 1986.

After ordination, Sis served as the associate pastor at Cristo Rey Church in Austin, Texas from 1986 to 1988 and as associate pastor in campus ministry at the St. Mary’s Student Center in College Station, Texas in 1989. From 1990 to 1992 he served as the associate pastor at St. Mary’s Cathedral in Austin, and returned to St. Mary’s Student Center as associate pastor in 1992 and served there as pastor from 1993 to 2006. He then served as the vocation director for the Diocese of Austin from 2006 to 2009. He served as the pastor of St. Thomas More Church in Austin (2009–2010) before serving as the vicar general and moderator of the curia of the Austin Diocese from 2010 to 2013.

SIS on Wikipedia

Random information on the term “PAPA”:

Papa is a nickname which may refer to:

PAPA on Wikipedia

Random information on the term “DAD”:

Dad (Hungarian pronunciation: [dɒd]) is a village in Komárom-Esztergom county, Hungary.

The village is located on the north eastern part of the Vértes Mountains. It is located some 80 km (50 mi) away from the capital, and some 18 km (11 mi) away from the county capital.

DAD on Wikipedia

Random information on the term “MAMA”:

A mama-san or mamasan is usually a woman in a position of authority, especially one in charge of a geisha house or bar or nightclub in Japan and East Asia.

The term is also used to refer to a woman who works in a supervisory role in certain establishments in Southeast Asia, typically those related to drinking places. Papa-san may be used to refer to a man in a similar position.

The term is a combination of the English word “Mama” and the Japanese suffix -san which is a polite honorific attached to a person’s name or title, coined by U.S. soldiers in Japan after World War II. This probably has had some influence in its spread to other Southeast Asian countries.

The term mama-san in Japanese is not a polite reference to a mother and should never be used as such. Most Japanese children today call their mother mama, but the term does not persist into adulthood. The way to refer to one’s mother, in Japanese, is okaa-san.

It is considered extremely rude to refer to a woman in charge of a respectable restaurant or inn as mama-san. The proper title for her is okami or okami-san.

MAMA on Wikipedia

Random information on the term “MOM”:

Mom is an upcoming Indian thriller film directed by Ravi Udyawar and produced by Boney Kapoor, Sunil Manchanda, Mukesh Talreja, Naresh Agarwal and Gautam Jain. The film stars Sridevi, Akshaye Khanna, Abhimanyu Singh, Sajal Ali, Adnan Siddiqui and Nawazuddin Siddiqui.

The film is stated to release on 7 July 2017 in four languages.

It was announced in early 2016 that Sridevi would be starring next in Boney Kapoor’s woman-centric home-production titled Mom to be directed by Ravi Udyawar. Nawazuddin Siddiqui was cast to play an important role in the film and the actor revealed that it was a dream come true for him to work with Sridevi. Subsequently, Akshaye Khanna and actors Sajal Ali and Adnan Siddiqui were cast in crucial roles. A. R. Rahman was signed to compose the music of Mom.

The first spell of film was shot in New Delhi in March 2016 around locations of Shri Ram College of Commerce in Delhi University and Noida Film City. Following this, Mom was shot in an extensive schedule in Mestia, Georgia. The crew shot in freezing conditions of minus seven degrees for over two months. Despite the challenging climactic environment, the schedule was successfully wrapped up. Shooting resumed once more in March 2017 and the last leg of the film was completed in Bangkok.

MOM on Wikipedia

Random information on the term “UNCLE”:

Napoleon Solo is a fictional character from the 1960s TV spy series The Man from U.N.C.L.E. The series was remarkable for pairing the American Solo, played by Robert Vaughn, and the Russian Illya Kuryakin as two spies who work together for an international espionage organisation at the height of the Cold War.

Solo possesses a charm, sophistication, efficiency, and weakness for beautiful women comparable to Bond’s. But Solo is considerably less intense and also less brutal than the British Secret Service agent, and he possesses a laid-back ease that recalls the young Cary Grant. The show’s original concept had Solo as a Canadian; but he is consistently American in the show.

Solo is Number One in Section Two (Operations and Enforcement) at U.N.C.L.E. (In the first season he wore a badge with the Roman numeral II designating him as head of Section Two. During the switch to color in the second season, new badges were created and Robert Vaughn, mistaking the earlier II for an eleven, chose the wrong badge number for Solo.) It was originally intended that Solo would be the primary focus of the series, however the unexpected popularity of the Russian agent, Illya Kuryakin, played by David McCallum, saw McCallum elevated to co-star status. Most of the episodes devote equal screen time to Kuryakin and Solo, and much of the success of the program was based on the chemistry between McCallum and Vaughn.

UNCLE on Wikipedia

Random information on the term “SIB”:

Al-Seeb, As Seeb or As Sib (Arabic: السيب‎‎) is a coastal fishing city, located several kilometres northwest of Muscat, in northeastern Oman. As of the 2003 census, it had a population of 221,115.

Landmarks include the Naseem Garden, the Royal Stables and Equestrian Centre, Royal Guard of Oman Technical College, the Bait al Baraka palace, Seeb International Airport and Markaz al Bahja.

Seeb has a hot desert climate (Köppen climate classification BWh) with very hot summers and warm winters. Precipitation is low, and falls mainly in the months from December to April.

In June 2014 the Register disclosed that Seeb is the location of a “beyond top secret” internet monitoring site.

Al Seeb Club and Al-Shabab are located in Seeb.

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Portuguese India

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Portuguese India

SIB on Wikipedia

Random information on the term “QUAD”:

Companies that manufacture equipment used for the amplification of audio signals, such as a signal emanating from a mixing console, DJ mixer or Compact Disc player in order to produce audible sound through loudspeakers.

This category has the following 4 subcategories, out of 4 total.

The following 84 pages are in this category, out of 84 total. This list may not reflect recent changes (learn more).

QUAD on Wikipedia

Random information on the term “CHILD”:

Congenital hemidysplasia with ichthyosiform erythroderma and limb defects (also known as “CHILD syndrome”) is a genetic disorder with onset at birth seen almost exclusively in females.:485 The disorder is related to CPDX2, and also has skin and skeletal abnormalities, distinguished by a sharp midline demarcation of the ichthyosis with minimal linear or segmental contralateral involvement.:501

The acronym was introduced in 1980.

The acronym CHILD stands for the symptoms of the syndrome:

CHILD syndrome is inherited in an X-linked dominant fashion and is associated with a mutation of the NSDHL gene. This gene encodes for the enzyme 3beta-hydroxy sterol dehydrogenase which catalyzes a step in the cholesterol biosynthetic pathway. Locations of this enzyme include the membranes of the endoplasmic reticulum and on the surface of intracellular lipid storage droplets. A shortage of the enzyme may allow potentially toxic byproducts of cholesterol production to accumulate in the body’s tissues. Mutations of the gene have been reported in all three types: missense, nonsense, and stop mutations, all resulting in loss of function of NSDHL. The type of mutation is not believed to be the underlining reason for clinical variations in the extent of involvement but rather the differences in the pattern of X inactivation. Although researchers suspect that low levels of cholesterol and/or an accumulation of other substances are responsible for disrupting the growth and development of many body parts, the precise rationale for the laterality of the syndrome has yet to be determined.

CHILD on Wikipedia