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Possible Answers:
LUX.
Last seen on: NY Times Crossword 25 Jan 20, Saturday
Random information on the term “LUX”:
Circadian Clock Associated 1 (CCA1) is a gene that is central to the circadian oscillator of angiosperms. It was first identified in Arabidopsis thaliana in 1993. CCA1 interacts with LHY and TOC1 to form the core of the oscillator system. CCA1 expression peaks at dawn. Loss of CCA1 function leads to a shortened period in the expression of many other genes.
CCA1 was first identified in Arabidopsis thaliana by Elaine Tobin’s lab in UCLA in 1993. Tobin’s lab was studying promoter fragments that contribute to light regulation of light-harvesting Chlorophyll A/B Binding Protein (LHCB), and noticed DNA-binding activity that had affinity for a specific light-responsive fragment of the LHCB promoter. This DNA-binding activity was designated as CA-1 because the binding is mostly to cytosine and adenine-rich sequences. They found that this binding activity is necessary for phytochrome response. They later found the gene responsible for this activity by screening the Arabidopsis expression library. CCA1 referred to the CA-1 clone, and now designated the gene responsible for this DNA binding activity. The evolution of circadian clocks in land plants is not understood, because circadian rhythms have received little attention in plants other than angiosperms.