Golden — (senior)

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Possible Answers:

AGER.

Last seen on: Premier Sunday – King Feature Syndicate Crossword – Dec 16 2018

Random information on the term “AGER”:

Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars.[1] They can be a factor in aging and in the development or worsening of many degenerative diseases, such as diabetes, atherosclerosis, chronic kidney disease, and Alzheimer’s disease.[2]

Animal-derived foods that are high in fat and protein are generally AGE-rich and are prone to further AGE formation during cooking.[3]

AGEs affect nearly every type of cell and molecule in the body and are thought to be one factor in aging and some age-related chronic diseases.[4][5][6] They are also believed to play a causative role in the vascular complications of diabetes mellitus.[7]

Under certain pathologic conditions, such as oxidative stress due to hyperglycemia in patients with diabetes,[8] and hyperlipidemia,[citation needed] AGE formation can be increased beyond normal levels. AGEs are now known to play a role as proinflammatory mediators in gestational diabetes as well.[9]

AGER on Wikipedia