“I messed up,” in slang

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Possible Answers:

MYB.

Last seen on: NY Times Crossword 8 Dec 19, Sunday

Random information on the term ““I messed up,” in slang”:

E or e is the fifth letter and the second vowel letter in the modern English alphabet and the ISO basic Latin alphabet. Its name in English is e (pronounced /ˈiː/), plural ees. It is the most commonly used letter in many languages, including Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Latvian, Norwegian, Spanish, and Swedish.

The Latin letter ‘E’ differs little from its source, the Greek letter epsilon, ‘Ε’. This in turn comes from the Semitic letter hê, which has been suggested to have started as a praying or calling human figure (hillul ‘jubilation’), and was most likely based on a similar Egyptian hieroglyph that indicated a different pronunciation. In Semitic, the letter represented /h/ (and /e/ in foreign words); in Greek, hê became the letter epsilon, used to represent /e/. The various forms of the Old Italic script and the Latin alphabet followed this usage.

Although Middle English spelling used ⟨e⟩ to represent long and short /e/, the Great Vowel Shift changed long /eː/ (as in ‘me’ or ‘bee’) to /iː/ while short /ɛ/ (as in ‘met’ or ‘bed’) remained a mid vowel. In other cases, the letter is silent, generally at the end of words.

“I messed up,” in slang on Wikipedia

Random information on the term “MYB”:

1GUU, 1GV2, 1GV5, 1GVD, 1H88, 1H89, 1IDY, 1IDZ, 1MBE, 1MBF, 1MBG, 1MBH, 1MBJ, 1MBK, 1MSE, 1MSF, 1SB0, 2AGH

4602

17863

ENSG00000118513

ENSMUSG00000019982

P10242Q708E1

P06876

NM_001161659NM_001161660NM_005375

NM_001198914NM_010848NM_033597

NP_001155131NP_001155132NP_005366

NP_001185843NP_034978

Myb genes are part of a large gene family of transcription factors found in animals and plants. In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper. Members of the extended SANT/Myb family also include the SANT domain and other similar all-helical homeobox-like domains.

The Myb gene family is named after the eponymous gene in Avian myeloblastosis virus. The viral Myb (v-Myb, P01104) recognizes the sequence 5′-YAACKG-3′. It causes myeloblastosis (myeloid leukemia) in chickens. Compared to the normal animal cellular Myb (c-myb), v-myb contains deletions in the C-terminal regulatory domain, leading to aberrant activation of other oncogenes.

MYB on Wikipedia