Prefix with system

This time we are looking on the crossword clue for: Prefix with system.
it’s A 18 letters crossword puzzle definition. See the possibilities below.

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Possible Answers: ECO.

Last seen on: –NY Times Crossword 9 Dec 21, Thursday
NY Times Crossword 21 Jul 20, Tuesday
NY Times Crossword 25 Mar 20, Wednesday
NY Times Crossword 8 Feb 20, Saturday