This time we are looking on the crossword clue for: Refine.
it’s A 6 letters crossword puzzle definition. See the possibilities below.
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Possible Answers: HONE, SMELT, TWEAK, RAREFY, IMPROVE, DISTILL.
Last seen on: –NY Times Crossword 12 Dec 21, Sunday
–LA Times Crossword 4 Nov 21, Thursday
–Wall Street Journal Crossword – July 22 2020 – Settle In
–Universal Crossword – Jun 6 2020
–NY Times Crossword 9 Nov 19, Saturday
–The Washington Post Crossword – Mar 22 2019
-The Washington Post Crossword – June 14 2018
–LA Times Crossword 14 Jun 2018, Thursday
-LA Times Crossword 8 Dec 2017, Friday
Random information on the term “TWEAK”:
Darbepoetin alfa (rINN) /dɑːrbəˈpɔɪtᵻn/ is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88,T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It has a 3-fold longer serum half-life compared to epoetin alpha and epoetin beta. It stimulates erythropoiesis (increases red blood cell levels) by the same mechanism as rHuEpo (binding and activating the Epo receptor) and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy. Darbepoetin is marketed by Amgen under the trade name Aranesp.
The drug was approved in September 2001 by the Food and Drug Administration for treatment of anemia in patients with chronic renal failure by intravenous or subcutaneous injection. In June 2001, it had been approved by the European Medicines Agency for this indication as well as the treatment of anemia in cancer patients undergoing chemotherapy.
Dr. Reddy’s Laboratories launched darbepoetin alfa in India under the brand name ‘Cresp’ in August 2010. This is the world’s first follow-on biologic of darbepoetin alfa. Visit www.cresp.in