Sedate, say

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Possible Answers:

DRUG.

Last seen on: Wall Street Journal Crossword – June 27 2020 – T Intersections

Random information on the term “DRUG”:

In medicine, a bolus (from Latin bolus, ball) is the administration of a discrete amount of medication, drug, or other compound within a specific time, generally within 1 – 30 minutes, in order to raise its concentration in blood to an effective level. The administration can be given by injection: intravenously, intramuscularly, intrathecally, subcutaneously, or by inhalation.[clarification needed] The article on routes of administration provides more information, as the preceding list of ROAs is not exhaustive.

The placement of the bolus dose depends on the systemic levels of the contents desired throughout the body. An intramuscular injection of vaccines allows for a slow release of the antigen to stimulate the body’s immune system and to allow time for developing antibodies. Subcutaneous injections are used by heroin addicts (called ‘skin popping’, referring to the bump formed by the bolus of heroin), to sustain a slow release that staves off withdrawal symptoms without producing euphoria.

DRUG on Wikipedia