Slangy suffix with "two"

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Possible Answers:

FER.

Last seen on: Premier Sunday – King Feature Syndicate Crossword – Sep 26 2021

Random information on the term “FER”:

Feronia, also known as FER or protein Sirene, is a recognition receptor kinase found in plants. FER plays a significant part in the plant immune system as a receptor kinase which assists in immune signaling within plants, plant growth, and plant reproduction. FER is regulated by the Rapid Alkalinization Factor (RALF). FER regulates growth in normal environments but it is most beneficial in stressful environments as it helps to initiate immune signaling. FER can also play a role in reproduction in plants by participating in the communication between the female and male cells. FER is found in and can be studied in the organism Arabidopsis thaliana.

Feronia (FER) has a taxonomic lineage as follows: Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliophyta > Eudicotyledons > Gunneridae > Pentapetalae > Rosids > Malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis.

FER on Wikipedia