Sore spot

This time we are looking on the crossword clue for: Sore spot.
it’s A 9 letters crossword puzzle definition. See the possibilities below.

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Possible Answers: ACHE, SCAB, PEEVE, ULCER, WELT, LESION, ABSCESS.

Last seen on: –NY Times Crossword 21 Jan 23, Saturday
Eugene Sheffer – King Feature Syndicate Crossword – Nov 28 2022
Thomas Joseph – King Feature Syndicate Crossword – Jul 19 2019
Newsday.com Crossword – Apr 28 2019
Newsday.com Crossword – Dec 26 2018
Newsday.com Crossword – Aug 22 2018
Newsday.com Crossword – Aug 19 2018
Newsday.com Crossword – Jun 17 2018

Random information on the term “ACHE”:

An acetylcholinesterase inhibitor (often abbreviated AChEI) or anti-cholinesterase is a chemical or a drug that inhibits the acetylcholinesterase enzyme from breaking down acetylcholine, thereby increasing both the level and duration of action of the neurotransmitter acetylcholine. Acetylcholinesterase inhibitors are classified as reversible, irreversible, or quasi-irreversible (also called pseudo-irreversible).

Acetylcholinesterase inhibitors:

Some major effects of cholinesterase inhibitors:

Administration of reversible cholinoesterase inhibitors is contraindicated with those that have urinary retention due to obstruction.

When used in the central nervous system to alleviate neurological symptoms, such as rivastigmine in Alzheimer’s disease, all cholinesterase inhibitors require doses to be increased gradually over several weeks, and this is usually referred to as the titration phase. Many other types drug treatments may require a titration or stepping up phase. This strategy is used to build tolerance to adverse events or to reach a desired clinical effect. This also prevents accidental overdose and is therefore recommended when initiating treatment with drugs that are extremely potent and/or toxic (drugs with a low therapeutic index).

ACHE on Wikipedia

Random information on the term “SCAB”:

Apple scab is a disease of Malus trees, such as apple trees, caused by the ascomycete fungus Venturia inaequalis. The disease manifests as dull black or grey-brown lesions on the surface of tree leaves, buds or fruits. Lesions may also appear less frequently on the woody tissues of the tree. Fruits and the undersides of leaves are especially susceptible. The disease rarely kills its host, but can significantly reduce fruit yields and fruit quality. Affected fruits are less marketable due to the presence of the black fungal lesions.

The infection cycle begins in the springtime, when suitable temperatures and moisture promote the release of V. inaequalis ascospores from leaf litter around the base of previously infected trees. These spores rise into the air and land on the surface of a susceptible tree, where they germinate and form a germ tube that can directly penetrate the plant’s waxy cuticle. A fungal mycelium forms between the cuticle and underlying epidermal tissue, starting as a yellow spot that grows and ruptures to reveal a black lesion bearing asexually as the conidia are released and germinate on fresh areas of the host tree, which in turn produce another generation of conidial spores. This cycle of secondary infections continues throughout the summer, until the leaves and fruit fall from the tree at the onset of winter.

SCAB on Wikipedia

Random information on the term “WELT”:

This list of tallest buildings in Fort Wayne ranks skyscrapers and high-rises in the U.S. city of Fort Wayne, Indiana, by height. The tallest building in the city is the 27-story Indiana Michigan Power Center, which rises 442 feet (135 m) and was completed in 1982. The building stands as the fourth-tallest building in Indiana and the tallest outside Indianapolis. It is also the tallest reinforced concrete building in Indiana. The city’s second-tallest building is PNC Center, which rises 339 feet (103 m). Of the 40 tallest buildings in Indiana, three are located in Fort Wayne. As of May 2015, there are two completed skyscrapers and ten completed high-rises in the city, with one under construction.

This list ranks buildings in Fort Wayne that stand at least 150 feet (46 m) tall, based on standard height measurement. This includes spires and architectural details but does not include antenna masts. An equal sign (=) following a rank indicates the same height between two or more buildings. The “Year” column indicates the year in which a building was completed.

WELT on Wikipedia