Syrup source

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Possible Answers: SAP, MAPLE, TREESAP, SORGO, SUGARMAPLE, MAPLETREE.

Last seen on: –L.A. Times Daily Crossword – Sep 5 2022
L.A. Times Daily Crossword – May 11 2022
Thomas Joseph – King Feature Syndicate Crossword – May 9 2022
Newsday.com Crossword – Feb 20 2022s
LA Times Crossword 15 Dec 21, Wednesday
USA Today Crossword – Dec 10 2021
NY Times Crossword 21 Jul 21, Wednesday
LA Times Crossword 12 Jul 21, Monday
LA Times Crossword 15 Dec 20, Tuesday
The Washington Post Crossword – Dec 15 2020
The Washington Post Crossword – Nov 8 2020
LA Times Crossword 8 Nov 20, Sunday
USA Today Crossword – Nov 9 2019
Universal Crossword – Jan 6 2019

Random information on the term “SAP”:

4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV

325

20219

ENSG00000132703

ENSMUSG00000026542

P02743

P12246

NM_001639

NM_011318

NP_001630

NP_035448.2
NP_035448

The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called “amyloid”. APCS is its human gene.

AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1-[6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl] pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP.

SAP on Wikipedia

Random information on the term “MAPLE”:

The following 19 pages are in this category, out of 19 total. This list may not reflect recent changes (learn more).

MAPLE on Wikipedia