“The gloves are off!”

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it’s A 21 letters crossword puzzle definition.
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Last seen on: Wall Street Journal Crossword Answers – January 14 2023 – Alternate Endings

Random information on the term “ITSON”:

Guaymas (Spanish pronunciation: [ˈwajmas]) is a city in Guaymas Municipality, in the southwest part of the state of Sonora, in northwestern Mexico. The city is 134 kilometres (83 mi) south of the state capital of Hermosillo, and 389 kilometres (242 mi) from the U.S. border. The municipality is located on the Gulf of California and the western edge of the Sonoran Desert and has a hot, dry climate and 117 kilometres (73 mi) of beaches. The municipality’s formal name is Guaymas de Zaragoza and the city’s formal name is the Heroica Ciudad de Guaymas.

The city proper is mostly an industrial port and is the principal port for the state of Sonora. The city has a well-attended annual carnival, which has been held since 1888. Nearby, San Carlos and its beaches are major tourist attractions.

Before the arrival of the Europeans, the bay of Guaymas was dominated by the Guaymas, Seri and Yaqui tribes. In 1539, two Spanish ships, the Santa Águeda and the Trinidad, arrived in Guaymas Bay. They were commanded by Francisco de Ulloa, who called the area “the port of ports.”

ITSON on Wikipedia