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Possible Answers:
SERT.
Last seen on: New York Times Crossword – Mar 9 2019
Random information on the term “SERT”:
5I6X, 5I73, 5I75, 5I6Z, 5I71, 5I74
6532
15567
ENSG00000108576
ENSMUSG00000020838
P31645
Q60857
NM_001045
NM_010484
NP_001036
NP_034614
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.[5] SERT is a type of monoamine transporter protein that transports serotonin from the synaptic cleft to the presynaptic neuron.[6]
This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications of the SSRI and tricyclic antidepressant classes.[7] It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.[8]