Western Indians

This time we are looking on the crossword clue for: Western Indians.
it’s A 15 letters crossword puzzle definition. See the possibilities below.

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Possible Answers: UTES, SACS, OSAGES, OTOS, REES, OTOES, IOWAS, ARAPAHOS, UTAHS, PAIUTES.

Last seen on: –Thomas Joseph – King Feature Syndicate Crossword – Mar 2 2020

Random information on the term “SACS”:

1IUR, 3O10

26278

n/a

ENSG00000151835

n/a

Q9NZJ4

n/a

NM_001278055
NM_014363

n/a

NP_001264984
NP_055178

n/a

Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. Sacsin is a Hsp70 co-chaperone.

This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. This modular protein is essential for normal mitochondrial network organization. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy.

SACS on Wikipedia