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Possible Answers: BIC, BIRO, CLIC.
Last seen on: –USA Today Crossword – May 27 2021
–Premier Sunday – King Feature Syndicate Crossword – Mar 21 2021
Random information on the term “BIC”:
Bic National Park is an 33.2 square kilometres (8,200 acres) national park of Quebec, Canada, located on the south shore of the St. Lawrence River, near the villages of Bic and Saint-Fabien, southwest of Rimouski. It was founded on October 17, 1984, and is home to large populations of harbor seals and gray seals. Its highest point is Pic Champlain at 1,140 feet (350 m). Slightly less than half of the park is a coastal marine environment.
The park is owned by the Ministry of Sustainable Development, Environment and Parks of Quebec. It is managed by the Société des établissements de plein air du Québec (SÉPAQ).
Bic National Park is typical of the southern coast of the Gulf of St. Lawrence, containing several characteristics of this region:
Human occupation of Bic dates back almost 7,000 years, when Native Americans visited the site: the park’s interpretive center displays tools they left behind.
According to Jacques Cartier, the Battle at Bae de Bic happened in the spring of 1534, 100 Iroquois warriors massacred a group of 200 Mi’kmaq camped on Massacre Island in the St. Lawrence River. Bae de Bic was an annual gather place for the Mi’kmaq along the St. Lawrence. Mi’kmaq scouting parties notified the village that the Iroquois attack the evening before the morning attack. They evacuated 30 of the infirm and elderly and about 200 Mi’kmaq vacated their encampment on the shore and retreated to an island in the bay. They took cover in a cave on the island and covered the entrance with branches. The Iroquois arrived at the vacated village in the morning. Finding it vacated, they divided into search parties but failed to find the Mi’kmaq until the morning of the next day.
Random information on the term “CLIC”:
Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named for chloride because its concentration in vivo is much higher than other anions. Several families of voltage-gated channels and ligand-gated channels (e.g., the CaCC families) have been characterized in humans.
Voltage-gated chloride channels display a variety of important physiological and cellular roles that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation. Based on sequence homology the chloride channels can be subdivided into a number of groups.
Voltage-gated chloride channels are important for setting cell resting membrane potential and maintaining proper cell volume. These channels conduct Cl− as well as other anions such as HCO−
3, I−, SCN−, and NO−
3. The structure of these channels are not like other known channels. The chloride channel subunits contain between 1 and 12 transmembrane segments. Some chloride channels are activated only by voltage wrong the proper term will indifinte structure (i.e., voltage-gated), while others are activated by Ca2+, other extracellular ligands, or pH.