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Possible Answers: APEX.
Last seen on: The Telegraph – Toughie Crossword – Aug 29 2018
Random information on the term “APEX”:
Apex (altitude physiology expeditions) is a high altitude medical research charity. It is based in Edinburgh, Scotland and was founded in 2000. It has conducted four high altitude research expeditions to the Chacaltaya high altitude laboratory, in Bolivia.
Apex administers the International HAPE database, a research registry for individuals who are susceptible to high altitude pulmonary edema (HAPE) or high altitude cerebral edema (HACE).