Clinch

This time we are looking on the crossword clue for: Clinch.
it’s A 6 letters crossword puzzle definition. See the possibilities below.

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Possible Answers: ICE, NAIL, SEWUP, GRAPPLE, NAILDOWN, SNUGGLESTRUGGLE.

Last seen on: –NY Times Crossword 14 Aug 22, Sunday
L.A. Times Daily Crossword – Jul 30 2022
Eugene Sheffer – King Feature Syndicate Crossword – May 11 2022
NY Times Crossword 31 Oct 21, Sunday
Wall Street Journal Crossword – February 21 2020 – Game Pieces
LA Times Crossword 19 Oct 19, Saturday
Eugene Sheffer – King Feature Syndicate Crossword – May 31 2019

Random information on the term “ICE”:

1BMQ, 1IBC, 1ICE, 1RWK, 1RWM, 1RWN, 1RWO, 1RWP, 1RWV, 1RWW, 1RWX, 1SC1, 1SC3, 1SC4, 2FQQ, 2H48, 2H4W, 2H4Y, 2H51, 2H54, 2HBQ, 2HBR, 2HBY, 2HBZ, 3D6F, 3D6H, 3D6M, 3E4C, 3NS7, 5FNA

834

12362

ENSG00000137752

ENSMUSG00000025888

P29466

P29452

NM_033294
NM_033295

NM_009807

NP_150636
NP_150637

NP_033937.2
NP_033937

Caspase-1/Interleukin-1 converting enzyme (ICE) is an evolutionarily conserved enzyme that proteolytically cleaves other proteins, such as the precursors of the inflammatory cytokines interleukin 1β and interleukin 18 as well as the pyroptosis inducer Gasdermin D, into active mature peptides. It plays a central role in cell immunity as an inflammatory response initiator. Once activated through formation of an inflammasome complex, it initiates a proinflammatory response through the cleavage and thus activation of the two inflammatory cytokines, interleukin 1β (IL-1β) and interleukin 18 (IL-18) as well as pyroptosis, a programmed lytic cell death pathway, through cleavage of Gasdermin D. The two inflammatory cytokines activated by Caspase-1 are excreted from the cell to further induce the inflammatory response in neighboring cells.

ICE on Wikipedia

Random information on the term “NAIL”:

A nail is a horn-like envelope covering the tips of the fingers and toes in most primates and a few other mammals. Nails are similar to claws in other animals. Fingernails and toenails are made of a tough protective protein called keratin. This protein is also found in the hooves and horns of different animals.

The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.

The matrix, sometimes called the matrix unguis, keratogenous membrane, nail matrix, or onychostroma, is the tissue (or germinal matrix) which the nail protects. It is the part of the nail bed that is beneath the nail and contains nerves, lymph and blood vessels. The matrix is responsible for producing cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the shape of the fingertip itself shows if the nail plate is flat, arched, or hooked. The matrix will continue to grow as long as it receives nutrition and remains in a healthy condition. As new nail plate cells are made, they push older nail plate cells forward; and in this way older cells become compressed, flat, and translucent. This makes the capillaries in the nail bed below visible, resulting in a pink color.

NAIL on Wikipedia