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Possible Answers: ASS, SAP, OAF, IDIOT, DOPE, CLOD, DOLT, SCHMO, BOOB, STUPE, SIMP, NITWIT, STUPID, DOOFUS, SCHNOOK.
Last seen on: –Newsday.com Crossword – Mar 19 2022s
–NY Times Crossword 29 Jul 20, Wednesday
–Wall Street Journal Crossword – July 22 2020 – Settle In
–The Washington Post Crossword – Jul 5 2020
–LA Times Crossword 5 Jul 20, Sunday
–NY Times Crossword 18 Jun 20, Thursday
-Thomas Joseph – King Feature Syndicate Crossword – Jun 11 2018
Random information on the term “ASS”:
The donkey or ass (Equus africanus asinus) is a domesticated member of the horse family, Equidae. The wild ancestor of the donkey is the African wild ass, E. africanus. The donkey has been used as a working animal for at least 5000 years. There are more than 40 million donkeys in the world, mostly in underdeveloped countries, where they are used principally as draught or pack animals. Working donkeys are often associated with those living at or below subsistence levels. Small numbers of donkeys are kept for breeding or as pets in developed countries.
A male donkey or ass is called a jack, a female a jenny or jennet; a young donkey is a foal. Jack donkeys are often used to mate with female horses to produce mules; the biological “reciprocal” of a mule, from a stallion and jenny as its parents instead, is called a hinny.
Asses were first domesticated around 3000 BC, probably in Egypt or Mesopotamia, and have spread around the world. They continue to fill important roles in many places today. While domesticated species are increasing in numbers, the African wild ass is an endangered species. As beasts of burden and companions, asses and donkeys have worked together with humans for millennia.
Random information on the term “SAP”:
4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV
325
20219
ENSG00000132703
ENSMUSG00000026542
P02743
P12246
NM_001639
NM_011318
NP_001630
NP_035448.2
NP_035448
The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called “amyloid”. APCS is its human gene.
AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1-[6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl] pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP.
Random information on the term “OAF”:
In human–computer interaction, computer accessibility (also known as accessible computing) refers to the accessibility of a computer system to all people, regardless of disability type or severity of impairment. The term “accessibility” is most often used in reference to specialized hardware or software, or a combination of both, designed to enable use of a computer by a person with a disability or impairment. Specific technologies may be referred to as assistive technology.
There are many disabilities or impairments that can be a barrier to effective computer use. These impairments, which can be acquired from disease, trauma, or may be congenital, include but are not limited to:
Accessibility is often abbreviated as the numeronym a11y, where the number 11 refers to the number of letters omitted. This parallels the abbreviations of internationalization and localization as i18n and l10n respectively.
People wishing to overcome an impairment in order to use a computer comfortably and productively may require a “special needs assessment” by an assistive technology consultant (such as an occupational therapist, a rehabilitation engineering technologist, or an educational technologist) to help them identify and configure appropriate assistive technologies to meet individual needs. Even those who are unable to leave their own home or who live far from assessment providers may be assessed (and assisted) remotely using remote desktop software and a web cam. For example, the assessor logs on to the client’s computer via a broadband Internet connection, observes the users computer skills, and then remotely makes accessibility adjustments to the client’s computer where necessary.
Random information on the term “DOPE”:
This category has the following 8 subcategories, out of 8 total.
The following 186 pages are in this category, out of 186 total. This list may not reflect recent changes (learn more).
This category contains only the following file.
Random information on the term “CLOD”:
The beef clod or shoulder is one of the cheapest cuts of beef and is taken from the shoulder region of the cattle. This is why it is sometimes called chuck or shoulder clod, because obviously “chuck” or “clod” means cheap, apparently. Beef clod consists of a large muscle system and some fat that covers the muscles. Beef clod can be prepared in a variety of methods both dry and moist, but the most recommended method to cook beef clod is to cook it with moist heat or braising. Long slow smoking also provides acceptable results.
Random information on the term “SIMP”:
Weakly interacting massive particles (WIMPs) are hypothetical particles that are thought to constitute dark matter. There exists no clear definition of a WIMP, but broadly a WIMP is a new elementary particle which interacts via gravity and any other force (or forces), potentially not part of the standard model itself, which is as weak as or weaker than the weak nuclear force, but also non-vanishing in its strength. A WIMP must also have been produced thermally in the early Universe, similarly to the particles of the standard model according to Big Bang cosmology, and usually will constitute cold dark matter. Obtaining the correct abundance of dark matter today via thermal production requires a self-annihilation cross section of
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{\displaystyle \langle \sigma v\rangle \simeq 3\times 10^{-26}\mathrm {cm} ^{3}\;\mathrm {s} ^{-1}}
, which is roughly what is expected for a new particle in the 100 GeV mass range that interacts via the electroweak force. Because supersymmetric extensions of the standard model of particle physics readily predict a new particle with these properties, this apparent coincidence is known as the “WIMP miracle”, and a stable supersymmetric partner has long been a prime WIMP candidate. However, recent null results from direct detection experiments including LUX and SuperCDMS, along with the failure to produce evidence of supersymmetry in the Large Hadron Collider (LHC) experiment has cast doubt on the simplest WIMP hypothesis. Experimental efforts to detect WIMPs include the search for products of WIMP annihilation, including gamma rays, neutrinos and cosmic rays in nearby galaxies and galaxy clusters; direct detection experiments designed to measure the collision of WIMPs with nuclei in the laboratory, as well as attempts to directly produce WIMPs in colliders, such as the LHC.
Random information on the term “STUPID”:
Stupid was a short-lived grouping of constructivist artists, formed in Cologne in 1919. The founding members were Willy Fick, Heinrich Hoerle and his wife Angelika Hoerle (1899–1923), Anton Räderscheidt and his wife Marta Hegemann, and Franz Wilhelm Seiwert.
The Stupid group aimed to address sociopolitical issues through an art of proletarian character. Seiwert and Räderscheidt had previously been active in the Cologne Dada scene, along with Max Ernst. Ernst later described Stupid as “a secession from Cologne Dada. As far as Hoerle and especially Seiwert were concerned, Dada’s activities were aesthetically too radical and socially not concrete enough”. Seiwert described the group’s esthetic: “We are attempting to be so clear that everyone will be able to understand us.”
Räderscheidt’s studio was their base of operations, but by 1920 he had abandoned the constructivist style. The group exhibited together and issued a publication, “Stupid 1”, before disbanding.